Application of laser particle size analyzer in nasal spray

Nasal spray is a type of preparation that is used directly in the nasal cavity to exert local or systemic therapeutic effects. It has rapid absorption, fast onset of action, can avoid the first-pass effect of the liver, has high bioavailability, and can bypass the blood-brain barrier to achieve brain targeting. advantage. Nasal spray uses a nebulizer to atomize solutions, sols, suspensions, and emulsions into small droplets, which are inhaled through the nose and deposited in the nasal cavity.

In the production process of nasal spray, particle size control is a very critical link. The particle size of the nasal spray directly affects the spray effect of the drug and the patient's experience. If the particle size is too large, the drug will easily form large particles when sprayed, which will be difficult to be absorbed by the nasal cavity, thereby affecting the efficacy of the drug; if the particle size is too small, the drug will easily form droplets when sprayed, which will be easily inhaled into the lungs, causing unnecessary side effects. Therefore, measuring and controlling the particle size of the nasal spray with a laser particle size analyzer can ensure the best spray effect of the drug and the best patient experience.

Measuring instrument information is as follows:

The video of measuring nanoparticles is as follows：