Application of laser particle size analyzer in bismuth subsalicylate

The particle size of bismuth subsalicylate has a certain impact on its effect, as follows:

Effect on drug dissolution and absorption

Advantages of small particle size: Bismuth subsalicylate powder with smaller particle size has a larger specific surface area, a larger contact area with gastrointestinal fluid, and a faster dissolution rate. It can release active ingredients faster and be absorbed by the human body faster, thereby faster Effectively exert its medicinal effect, quickly relieving gastric discomfort, indigestion, nausea and other symptoms.

Effect on drug distribution in gastrointestinal tract

Advantage of small particle size: Small particle size powder is easier to disperse evenly in the gastrointestinal tract, and can cover the surface of gastric mucosa and intestinal mucosa more extensively, forming a more complete protective film, effectively isolating the irritation of the mucosa by gastric acid, pepsin, etc. , better exert the protective effect of gastric mucosa, and is more effective in treating gastric ulcer, duodenal ulcer and other diseases1510.

Effects on drug binding to bacterial toxins

Small particle size advantage: Bismuth subsalicylate with small particle size can more fully contact and combine with bacterial toxins, enhance the adsorption capacity of bacterial toxins, and more effectively inhibit the activity of pathogenic microorganisms, thereby better alleviating the symptoms caused by bacterial infections. Symptoms such as diarrhea.

This time, Winner3003 is recommended to test basic salicylic acid secret samples for customers.

Measuring instrument information is as follows:

The video of measuring nanoparticles is as follows：